Week 5 of the 2025 NFL season starts with a Thursday Night Football game between two NFC West teams, the San Francisco 49ers and the Los Angeles Rams.
The game is set to take place at SoFi Stadium in Inglewood, California, where 49ers QB Mac Jones will face off against Rams QB Matthew Stafford.
Both teams are 3-1 this season as they continue their road to the playoffs in 2026 and Super Bowl LX.
Going into this week’s match, several 49ers players were injured, like QB Brock Purdy, who has been ruled out due to a toe injury. Other teammates out for the game include Jauan Jennings, Rick Pearsall, and George Kittle, who remains on the injury reserve list due to a hamstring.
What time is the game between the San Francisco 49ers and the Los Angeles Rams?
The NFL game between the San Francisco 49ers and the Los Angeles Rams is scheduled to start at 8:15 p.m. ET and 5:15 p.m. PT.
Where to watch and stream the San Francisco 49ers and the Los Angeles Rams game live?
Thursday Night Football is a night owned by Amazon’s Prime Video, where subscribers can livestream the game.
For fans in the playing teams’ local markets, they will be able to catch the action for free on their local over-the-air TV networks.
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Another free option is Amazon’s Twitch, where the game will stream on Prime Video’s channel.
NFL+ is another option for streaming the game on mobile devices. The streaming service has access to your local games and primetime games.
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