It’s nothing to be too freaked out over, but it is at least a little concerning that a fungal pathogen is apparently being tested out there that seems resistant to every antifungal drug it’s been hit with.
In a recent study published in Scientific Reports, scientists described the weird case of a 28-year-old woman in Kenya who developed a hospital-acquired surgical infection caused by a strain of Candidozyma auris that is to antifungal medication as bullets are to Superman. It shrugs off all four major classes of antifungal meds, including powerhouses like fluconazole and amphotericin B.
That’s evolution at work, and it’s only mildly terrifying. C. auris was already considered a pretty serious pathogen according to the World Health Organization, thanks to it being a fungus that calls hospitals its home and that it has a 30 to 50 percent mortality rate.
What Is ‘Pan-Drug Resistance’? A Rare Fungal Case in Kenya Is Raising Concern.
It’s not often that there is a pan- drug resistance thing out there making us all feel just a little bit freaked out by its mere presence in the world. This is the first time pan-drug resistance has been documented in Africa and only the second time in the world; the first time was in New York in 2022.
The Kenyan case is a little more worrying, as the Kenyan bug doesn’t share the same genetic mutations as the New York version. That means the fungus didn’t hop on a plane from New York to Kenya, which would have made sense. It became resistant to all four major antifungal drug classes entirely on its own in a completely different part of the world.
Right now, there doesn’t appear to be any immediate threat of this thing spreading, as the first line of defense is basic hygiene and strict hospital containment measures, but there is the bleak, perhaps overly anxious idea that immediately comes to mind: that this thing spreads and no modern medicine we currently have at our disposal can fight it.
Gulp.
The post Scientists Found a Fungal Strain Resistant to All Four Antifungal Drug Classes Tested appeared first on VICE.
