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Christina Applegate admits her debilitating MS battle has ‘broken’ her daughter: ‘I see it in her eyes’

August 27, 2025
in News
Christina Applegate admits her debilitating MS battle has ‘broken’ her daughter: ‘I see it in her eyes’
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Christina Applegate candidly revealed how her multiple sclerosis battle has “broken” her 14-year-old daughter, Sadie.

“I see her look at me when I’m in bed and can’t quite move, or I wanna go say goodnight to her in her room, but I can’t quite get down the hallway for whatever reason that my legs aren’t working that day,” she said on Tuesday’s episode of her “MesSy” podcast.

“Right now I can barely get to bathroom, it’s the worst, but that’s neither here nor there,” Applegate continued, adding, “It’s broken her.”

LOS ANGELES, CALIFORNIA - JANUARY 15:  Christina Applegate and daughter, Sadie LeNoble pose before attending the 75th Primetime Emmy Awards on January 15, 2024 in Los Angeles, California. (Photo by John Shearer/Getty Images for ABA)
Christina Applegate candidly admitted that she believes her MS diagnosis has “broken” her daughter, Sadie. Getty Images for ABA
LOS ANGELES, CALIFORNIA - FEBRUARY 26: (L-R) Christina Applegate and Sadie Grace LeNoble attend the 29th Annual Screen Actors Guild Awards at Fairmont Century Plaza on February 26, 2023 in Los Angeles, California. (Photo by Frazer Harrison/Getty Images)
“I see her look at me when I’m in bed and can’t quite move,” Applegate shared on her “MesSy” podcast Tuesday. Getty Images

The “Married… With Children” alum reflected on her life before her 2021 diagnosis, saying her daughter “only” knew her as “healthy, and a runner, and a Pelotoner and a dancer.”

“So then when this came about, 2021, she was like stoic about it,” Applegate continued.

“She didn’t know this. It was like losing the mom she had to this f–king thing. And the more she’s gotten older now, I think the more it’s hurting her.”

Applegate, 53, noted that it was a dramatic transition for both herself and the teen. She also explained the household was experiencing the effects of the COVID-19 pandemic around the same time.

The “Married… With Children” alum explained that prior to her 2021 diagnosis, her daughter “only” saw her as “healthy.” Getty Images for Critics Choice Association
US actress Christina Applegate arrives onstage during the 75th Emmy Awards at the Peacock Theatre at L.A. Live in Los Angeles on January 15, 2024. (Photo by Valerie Macon / AFP) (Photo by VALERIE MACON/AFP via Getty Images)
“It was like losing the mom she had to this f–king thing. And the more she’s gotten older now, I think the more it’s hurting her,” Applegate reflected. AFP via Getty Images

“We had just gone through COVID and no school and all this stuff and now mommy can’t do all the things that she used to be able to do and I see it in her eyes. I see it,” she admitted.

Still, the actress expressed gratitude to have her daughter by her side through her difficult times.

“But you know what’s really beautiful? When we’re out, she knows I’m having such a hard time because I have such anxiety about being out. And she’s always got my arm,” Applegate said.

“She’s always trying to help me through and help me with my cane and and all this stuff. At home, she’s like, ‘Can you please go down and make my food cause you’re the only one who can make it?’”

US actress Christina Applegate (R) and daughter Sadie Grace LeNoble pose for photos with Applegate's newly unveiled Hollywood Walk of Fame star in Hollywood, California, on November 14, 2022. (Photo by VALERIE MACON / AFP) (Photo by VALERIE MACON/AFP via Getty Images)
Still, Applegate expressed her gratitude to have her daughter’s help and support on her difficult days. AFP via Getty Images
LOS ANGELES, CALIFORNIA - JANUARY 15: (L-R) Sadie Grace LeNoble and Christina Applegate attend the 28th Annual Critics Choice Awards at Fairmont Century Plaza on January 15, 2023 in Los Angeles, California. (Photo by Matt Winkelmeyer/Getty Images for Critics Choice Association)
“When we’re out, she knows I’m having such a hard time because I have such anxiety about being out. And she’s always got my arm,” Applegate said. Getty Images for Critics Choice Association

Since sharing her diagnosis in August 2021, the “Dead to Me” actress has been candid about her health journey, giving her fans updates on her shared podcast with Jamie-Lynn Sigler.

Earlier this month, Applegate revealed that she was recently hospitalized with “so much pain” that had her “screaming.”

On the Aug. 5 episode of their podcast — which she recorded from her hospital bed in Los Angeles — she told listeners she had an infection in both of her kidneys.

The post Christina Applegate admits her debilitating MS battle has ‘broken’ her daughter: ‘I see it in her eyes’ appeared first on Page Six.

Tags: Celebrity Childrencelebrity familiescelebrity illnessescelebrity momschristina applegatePodcasts
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