South Park trolled Elon Musk on Tuesday with an X post calling out his ketamine use.
Harkening back to last week’s episode, “Sickofancy,” which mocked tech CEOs and their cozying up with the White House since Donald Trump’s win, the show’s official X account posted a meme with its character Randy Marsh holding a ketamine nasal spray with the message, “Just like any tech company, we are expanding our minds by microdosing ketamine.”
The account added alongside the meme, “Randy knows the real secret to becoming a tech mogul.”
Randy knows the real secret to becoming a tech mogul. pic.twitter.com/O83ibSvNCe
— South Park (@SouthPark) August 26, 2025
Musk was open about his ketamine use in an interview with Don Lemon last year, telling the former CNN host that he takes “a small amount once every other week or something like that.” He’s previously expressed support for using ketamine to treat depression.
In the South Park episode, Randy Marsh becomes convinced, through his overuse of ChatGPT, that he must microdose ketamine with nasal spray if wants to take his failing marijuana business “to the next level” and “be like those Silicon Valley elites.”


However, the Tesla CEO was only roasted indirectly in South Park’s last episode—unlike Tim Cook or Mark Zuckerberg, who appeared to deliver Trump’s shiny gifts. This is despite the fact that Musk’s name became synonymous with ketamine after The New York Times reported he took so much of the drug on the campaign trail with Trump that it affected his bladder. That report also alleged Musk regularly took ecstasy and psychedelic mushrooms.

But while Musk has not explicitly appeared in South Park’s explosive new season, he did actually voice himself in three episodes of the show’s 20th season in 2016.
Based on past references he’s made to the series, Musk appears to be a fan, though whether or not he will remain one is an open question now that the series creators’ are roasting his ketamine use and has taken a scathing stance against Trump, who Musk spent $290 million to get into office.
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