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‘The Morning Show’ star reveals his strict and ‘exhausting’ regimen for living with depression

June 8, 2025
in News
‘The Morning Show’ star reveals his strict and ‘exhausting’ regimen for living with depression
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Mark Duplass confessed that dealing with his depression and anxiety can be a grind.

“It’s a really complicated system of making sure you get enough sleep, making sure you get exercise every day, making sure I’m being really careful about the medication I take, never to miss it,” the “Morning Show” star told Page Six exclusively at the Gotham Television Awards earlier this week.

The 48-year-old actor explained that he’s been on the same medication for close to two decades and “it’s a very fundamental critical part of my system.”

Mark Duplass.
Mark Duplass shared how he handles his depression and anxiety. markduplass/Instagram
Mark Duplass.
The actor spoke to Page Six at the Gotham Television Awards. Getty Images
The “Morning Show” star has been open about his struggles on Instagram. ©Apple TV/Courtesy Everett Collection

He further admitted that “it’s a delicate balance and ecosystem.”

“I feel like I gotta make sure I keep showing up and working and it’s exhausting sometimes, but what choice do I have?”

The indie filmmaker has been honest about his mental health on Instagram for several years.

In October 2023, he posted a photo of himself, broadly smiling on a red carpet, as he opened up about his battle with depression and anxiety.

Duplass shared that he makes sure he eats well, gets enough sleep and takes his medication. ©Apple TV/Courtesy Everett Collection
Mark Duplass.
He called it a “delicate balance and ecosystem.” Getty Images for SAG-AFTRA

“I have been struggling with anxiety and depression for most of my life,” he wrote in the caption. “When I see pictures of myself like this one, I can see the fear and sadness behind the smile. Even at my most ‘happy’ times. But at times like these, when the world is so deeply terrifying and saddening, it’s a struggle just to stay on my feet and keep from crashing.”

Duplass said that he has always been open about his mental health struggles with friends and family but after posting, realized that the subject is not as “demystified” as he had previously believed.

Once the post went viral, the “Creep” star said that he felt that “this is a torch that’s probably worth carrying now, so then I became much more consciously forward and sharing.”

Mark Duplass.
The “Creep” star has previously said that “it’s a struggle just to stay on my feet and keep from crashing.” ©Netflix/Courtesy Everett Collection / Everett Collection
Mark Duplass.
Duplass believes his depression is tied to his creativity. Getty Images for SAG-AFTRA

Duplass explained that one of the perplexing things about dealing with depression is that “it’s not always rational when it comes.

“There can be times when things around you seem really bad and you’re doing well. There can be times when everything’s going really, really well and you can’t get out of bed. And that’s part of the confusing part of this thing, is, you know, why it hits and when.”

Despite all this, the “Penelope” co-creator believes that his depression and anxiety are “tied to my creativity and the way that my brain works.”

“So I wouldn’t change it,” he added, “but it’s not easy.”

The post ‘The Morning Show’ star reveals his strict and ‘exhausting’ regimen for living with depression appeared first on Page Six.

Tags: actorscelebrity illnessescelebrity interviewsdepressionExclusivegotham awardsMark DuplassMental Health
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