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Eric Dane reveals whether he will keep acting after ‘Brilliant Minds’ role

December 3, 2025
in News
Eric Dane reveals whether he will keep acting after ‘Brilliant Minds’ role

Eric Dane has no plans to stop acting as he battles amyotrophic lateral sclerosis (ALS).

The actor clarified in a Tuesday panel discussion put on by I Am ALS and “Brilliant Minds” that he will take on “ALS-centric” roles in the future because he is “fairly limited in what [he] can do physically.”

“I still have my brain, and I still have my speech,” he explained, noting that he is “willing to do just about anything.”

Eric Dane on virtual panel Tuesday
Eric Dane set the record straight on his acting future in a virtual panel on Tuesday. https://www.iamals.org/
Eric Dane arriving at Los Angeles International Airport in a wheelchair.
The “Grey’s Anatomy” alum will continue taking “ALS-centric” roles. BACKGRID

Dane, 53, added, “It’s going to be very difficult for me to play any other role where. … You know, look at the 800-pound gorilla in the room. I’m fine with that.”

The “Grey’s Anatomy” alum, who went public with his diagnosis in April, said he is “grateful” to “still work in any capacity.”

He made headlines last month for his role in “Brilliant Minds” as Matthew, a firefighter struggling to tell his family about his ALS.

Eric Dane in a wheelchair with Rebecca Gayheart and Georgia Dean walking behind him.
Dane noted he is “fairly limited” in what he can do onscreen. ALEXJR / BACKGRID
Zachary Quinto as Dr. Oliver Wolf, Eric Dane as Matthew Ramati, and Mädchen Amick as Alicia Ramati in
The “Euphoria” star is “grateful” to still be working. Pief Weyman/NBC

Dane reflected on this opportunity Tuesday, saying, “I’ve never played a character who’s going through something and something I’m dealing with in real time, in real life as well. So it was hard and there were moments where it was very difficult for me to even get the lines out.

“But overall, I was really grateful for the experience,” the “Euphoria” star continued, calling it “cathartic.”

He credited creator Michael Grassi and writer Daniela Lamas for being “so great” and “sort of shepherding along this tired old actor can barely speak.”

Zachary Quinto as Dr. Alex Wolf and Eric Dane as Robert Mantle in
His most recent role was in a “Brilliant Minds” episode last month. Pief Weyman/NBC
Eric Dane as Matthew Ramati in
Playing a character with ALS was a “cathartic” experience for Dane. Pief Weyman/NBC

Dane gushed, “[They] put me into a position for great success, and I’m grateful for them for that.”

The role marked the first show he has filmed since being diagnosed.

Grassi told USA Today last week about the unprecedented way Dane was honored on set.

“I have never seen this happen in my entire career, but he essentially got a 10-minute standing ovation after shooting that scene, because it was so beautiful and so honest and so real,” he revealed.

Eric Dane in a navy
“There were moments where it was very difficult for me to even get the lines out,” he said. iamalsorg/Instagram
Eric Dane in a wheelchair with a woman holding a blanket.
The 53-year-old went public with his diagnosis in April. BACKGRID

Grassi highlighted how “vulnerable” and “really important” it was for Dane “to come out and share this part of [him]self” publicly.

Dane gave a rare health update during the virtual panel, saying he “has no reason to be in a good spirit” but maintains a “buoyant” attitude.

“I don’t think anybody would blame me if I went upstairs in my bedroom, crawled under the sheets and spent the next two weeks crying,” he said. “I was a little bit pleasantly surprised when I realized that I wasn’t built like that because I thought for sure that was gonna be me.”

The post Eric Dane reveals whether he will keep acting after ‘Brilliant Minds’ role appeared first on Page Six.

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