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Vanessa Williams admits to ‘game changer’ Mounjaro use: ‘I want to look my best’

January 13, 2026
in News
Vanessa Williams admits to ‘game changer’ Mounjaro use: ‘I want to look my best’

Vanessa Williams is managing her menopause struggles with GLP-1 medication.

The “Ugly Betty” alum has been using Mounjaro for the past two years, she told Hello! magazine in a cover story published Monday.

“It’s a game‑changer,” she shared. “When I turned 60, I was like: ‘I want to be here for a long time, and I want to look my best. So what am I going to do?’”

Vanessa Williams at the after-party for the 1st anniversary of
Vanessa Williams has been using a GLP-1 medication for two years. Alan Chapman/Dave Benett/Getty Images
Vanessa Williams smiles on the cover of Hello Magazine, wearing a black blazer.
The actress said she uses Mounjaro in an interview with Hello! magazine. Hello Magazine

Williams, 62, started to struggle with maintaining her health after experiencing hormonal changes in her late 40s.

“My fifties were hard,” she said. “I started perimenopause in my late forties but suddenly, at 51, it’s crazy how your body changes.”

The Miss America winner admitted to feeling “out of control” of her own body.

Vanessa Williams at the Powerlist Black Excellence Awards.
“It’s a game‑changer,” she said of the medication. Lucy North/PA Images/INSTARimages
Vanessa Williams attends
Williams felt like she lost control of her body after starting perimenopause in her late 40s. Getty Images

“Because you’re working out the same way, eating the same, and your body is not reacting the way it used to,” she said.

Williams isn’t above using medication to feel her best.

“Science is amazing,” she gushed. “I’m like: ‘What’s next? Bring it on!’”

The Tony winner also copped to using Hormone Replacement Therapy (HRT) to help with menopause, as well as nicotinamide adenine dinucleotide injections (NAD+) to support cellular rejuvenation.

Vanessa Williams in a shimmering champagne dress, with arms outstretched, standing between a stained-glass window and a teal vase on a stand.
“It’s crazy how your body changes,” she said. vanessawilliamsofficial/Instagram
Vanessa Williams in a hat, holding an ice cream cone by the ocean.
The West End star said that her 50s “were hard.” vanessawilliamsofficial/Instagram

To maintain her youthful glow, she tried a facial treatment called P5, which is an updated version of the “vampire facial,”and involves polynucleotides and hyaluronic acid.

“I’ve done it three times and definitely see a difference,” she said

Williams also uses a hand-held Ziip device on her face, which can help tighten, plump and contour skin.

“It was created by the make-up artist Melanie Simon, who I worked with when I was doing ‘Desperate Housewives,’” she said. “She sent me one and I’ve been using it for 15 years.” 

Vanessa Williams smiling and making a peace sign on a boat.
“Science is amazing. I’m like: ‘What’s next? Bring it on!’” she said. vanessawilliamsofficial/Instagram
Vanessa Williams poses with a Pimm's drink at Wimbledon.
Williams also does P5, HRT and NAD+ injections. Getty Images for Pimm’s

For Williams, aging isn’t all bad.

“There’s an ease and wisdom that comes with age. It’s just delightful to still be in the game,” she said of her thriving acting career.

Williams is currently starring as Miranda Preistley in the West End musical production of “The Devil Wears Prada.”

The post Vanessa Williams admits to ‘game changer’ Mounjaro use: ‘I want to look my best’ appeared first on Page Six.

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